ESRP was founded in 2012 from fructification of years of extensive collaboration between the animal facilities of the University of Caen (CURB, headed by Dr Benoit Haelewyn), the INSERM unit UMR-S U919 “Serine Proteases and Pathophysiology of the Neurovascular Unit” and the addition of complementary skills of its 3 co-founders: Dr. Cyrille Orset, Dr. Benoit Haelewyn and Pr. Denis Vivien).

ESRP governance
is ensured by the administrative and scientific boards.

·     The administrative board is composed by 6 members including the ESRP scientific director (C. orset), the administrative director (B. Haelewyn), and 4 external members: Pr. Renaud Tissier from Paris (Professor in pharmacology, Ecole Nationale Vétérinaire d'Alfort), Pr. Emmanuel Touzé from Caen (neurologist, Director of the stroke-unit, Caen Hospital), Laurent Potier from Paris (Operational manager of the Longevity Institute) and a representative of the Caen University.

·      The scientific board is composed of 5 members including the ESRP scientific director (C. orset), 2 international experts in the field of stroke, Pr. Denis Vivien (co-founder of ESRP) and Dr. Joan Montaner (Neurologist, Barcelona, Spain), 1 expert in functional recovery, Pr. Thomas Fréret (Professor in pharmacology, Caen), and Dr. Clément Gakuba (anaesthesit, Caen Hospital).

The ESPR team
is composed of 1 assistant professor, 1 research engineer, 1 technician and 1 PhD student who is in charge of the development of innovative models of stroke. In addition, ESRP receives support form 5 zoo-technicians and 1 administrative person form the CURB.

As a department of the CURB, ESRP has full access of its infrastructure (1000m2), logistic and its experience in animal production, breeding and housing (rodent to primate). Since 2012, ESRP had invested in surgical devices (operating microscopes, physiological monitoring devices including flow Doppler, stereotaxic devices etc…) for 3 surgical theatres corresponding to 4 fully equipped benches. Furthermore, ESRP has a central position in the local scientific campus with direct connections to the platform of in vivo imaging (CYCERON), the behavioural research platform (BRP) and the INSERM UMR-S 919 allowing the realization of large-scale project including medical imaging (MRI, PETscan), functional evaluation and tissue analysis (histology, immunohistochemistry, molecular biology etc…)

ESRP is now clearly identified for its expertise in animal models of stroke, especially with the development of a reference model in mice (Orset et al., 2007) and is the only experimental platform dedicated to pre-clinical studies in stroke with national French label from the GIS IBISA. Now, ESRP has gained international recognition with the integration of the MULTIPART consortium (Multicentre Preclinical Animal Research Team; FP7) which promotes multicentric preclinical studies in stroke (


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